--- product_id: 715574302 title: "Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats with 1% Hydrocortisone, 1.25oz" brand: "zymox" price: "996 kr" currency: NOK in_stock: true reviews_count: 5 url: https://www.desertcart.no/products/715574302-advanced-formula-otic-plus-enzymatic-ear-solution-for-dogs-cats store_origin: NO region: Norway --- # 1% Hydrocortisone for soothing itch & redness 1.25 oz gentle, no pre-cleaning ear solution LP3 Enzyme System for deep biofilm penetration Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats with 1% Hydrocortisone, 1.25oz **Brand:** zymox **Price:** 996 kr **Availability:** ✅ In Stock ## Summary > 🐾 Clear ears, happy pets—because they deserve the best! ## Quick Answers - **What is this?** Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats with 1% Hydrocortisone, 1.25oz by zymox - **How much does it cost?** 996 kr with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.no](https://www.desertcart.no/products/715574302-advanced-formula-otic-plus-enzymatic-ear-solution-for-dogs-cats) ## Best For - zymox enthusiasts ## Why This Product - Trusted zymox brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Dual-Action Comfort:** 1% Hydrocortisone soothes itching and redness while fighting germs - • **No Pre-Cleaning Needed:** Gentle application avoids painful ear trauma—perfect for sensitive pets - • **Vet-Trusted Since 1998:** Clinically proven formula backed by decades of veterinary expertise - • **Biofilm-Busting Enzymes:** Patented LP3 system penetrates stubborn ear biofilms for lasting relief - • **Cruelty-Free & Made in USA:** Ethical, high-quality care you can trust for your furry family ## Overview Zymox Advanced Formula Otic Plus is a veterinarian-recommended enzymatic ear solution for dogs and cats of all ages. Featuring a patented LP3 Enzyme System, it effectively penetrates and breaks down biofilms caused by bacteria, fungi, and yeast without the need for pre-cleaning. Enhanced with 1% Hydrocortisone, it soothes itching and redness, providing fast, gentle relief. This 1.25 oz cruelty-free formula is proudly made in the USA and trusted by pet owners since 1998. ## Description Trusted by Veterinarians since 1998. ZYMOX Ear Solution with hydrocortisone aids in managing problematic ears on all animals including dogs and cats of any age. The patented LP3 Enzyme System delivers a potent formula to maximize the power of this product, without traumatic pre-cleaning and application. Otic Plus system works to penetrate deeper into the underlying bacteria's protective biofilm.1% Hydrocortisone is added for comfort. Use once daily for 7 to 14 days. For maintaining clean and healthy ears after the course of Ear Solution, use ZYMOX Ear Cleanser weekly. This product is proudly made in the USA. Animal Cruelty-Free and is never tested on animals. Item dimensions; 1.88"L x 1.13"W x 3.88"H, 1.25 Fluid Ounces (37ml). ## Features - Cat and dog ear cleaner, soothes recurrent ear issues, itching and redness, for pets of all ages - Relief from stubborn ear problem-causing microorganisms that form complex, irritating biofilms - Gentle formula helps relieve painful ear issues caused by resistant germs, fungi and yeast - Pet ear solution, no pre-cleaning of painful ears needed; safe, natural alternative to medication - LP3 Enzyme System to help clear ear exudate; 1% Hydrocortisone for itchy ears ## Technical Specifications | Specification | Value | |---------------|-------| | Allergen Information | Abalone Free | | Asin | B0066VLPGA | | Batteries Included | No | | Batteries Required | No | | Best Sellers Rank | #13,765 in Pet Supplies (See Top 100 in Pet Supplies) #46 in Dog Ear Care #354 in Cat Health Supplies | | Color | Original Version | | Customer Reviews | 4.7 4.7 out of 5 stars (14,326) 4.7 out of 5 stars | | Date First Available | 16 October 2013 | | Item Model Number | 441125 | | Item Weight | 36.8 g | | Number Of Items | 1 | | Pet Life Stage | All Life Stages | | Pet Type | Cat, Dog, Kitten, Pet, Puppy | | Product Dimensions | 19.69 x 10.8 x 9.53 cm; 36.85 g | | Quantity | 1 | | Size | 1.25 Fl Oz(Pack of 1) | | Specific Uses | EAR | ## Images ![Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats with 1% Hydrocortisone, 1.25oz - Image 1](https://m.media-amazon.com/images/I/512WnsXPqIL.jpg) ## Questions & Answers **Q: How is Zymox Plus different from Zymox (with the blue label)? both say 1.0 hydrocortisone.** A: My veterinarian said just to use the regular Zymox. It’s $10 cheaper and has the exact same ingredient. I looked it up myself. You can see the active ingredient in the inactive ingredient. Everything is the same. It’s kind of like the namebrand Excedrin. They they packaged their product in different ways. They have Excedrin for headaches Excedrin for migraine. Exactly the same product. A lot of companies do that apparently. Hope this helps **Q: how do you get all the wax off the inside of the ears where it flushes out from the ear drops** A: This is a bit thicker, kind of like the consistency of neosporin, so if your dogs ears are really wax-y right now, I would suggest doing a light cleaning before putting this in the ears. Once you put the zymox into the ear, rub your dogs ears kind of in a circular motion to help massage the solution down into the ear canal, and then just let it sit and do it's thing. Over time there will be less wax build up to clean out before applying the ointment. I now put it in my dogs ears about once every 10 to 15 days, just as maintenance and care, without needing any wax clean up before hand or afterwards. **Q: Is this supposed to be liquidy/thin like water (not thick)? What I received is a different consistency than the thicker regular zymox I'm used to.** A: I ordered and received a bottle this week and the solution is much thinner than the previous zymox plus otic-hc advanced formula bottles I've ordered. I haven't used it yet but just by shaking the bottle I can tell it is very liquidy compared to the bottle I have left over. I also compared the boxes and the box I received this week looks different as well. The font is different and the box has a different texture. I also read the paper inside and noticed a major typo on the one I just received. Instead of spelling "externa" they spelled "exernna" 🤦🏽‍♀️ The boxes have different lot numbers and the box that I have already opened has a later expiration date than the box I just received. I hope they didn't send me a knock off. This enzymatic solution usually works wonders on my Boxer and completely cures her ear infections when I use it as directed. I will update you on the effectiveness of the bottle I just received after I use it. **Q: is this the same as Mometamax 15g** A: No Different item Mometamax is stronger and is prescription medication. ## Customer Reviews ### ⭐⭐⭐⭐⭐ This WORKS!!! Better, faster and cost less than the MONTHS of failed treatments at the Vet. *by on Reviewed in the United States 31 August 2026* Sorry if this takes a minute: I am a RN. My go-to is to trust what a MD or, in turn, a Vet tells me. However… We went through months and thousands $$$ treating and testing my dog’s ear infection with little improvement. It got to be so bad he started to shirk away when we approached him (it absolutely broke my heart!) We finally found the right Rx but it was a nightmare!!!Here we are a couple years later and we adopt a pair of cats from a local rescue group. Take them to our Vet for a new owner/bringing home check up and lo n behold one of them has ears full of dark brown nasty gunk, totally red and inflamed. Take cultures, NO mites, +staph (of course) +fungal/yeast overgrowth, same exact cultures that popped positive with my dog, except the issue is… The med they had given my dog that FINALLY worked, not available for kitties! They cleaned him up the best they could and I went home telling them I wanted to do more research…I found this stuff and gave it a Hail Mary shot after reading the multiple attestations of cures all over the internet. I was NOT exceedingly hopeful of a fix, just thinking it’d tide him over while I found a true “cure”. Ha!!!He was so inflamed originally I couldn’t get a starter picture, just imagine his ears practically PACKED with dark brownish-black, thick, cheesy, gunk, the Vet started out by scraping chunks out with a rubber speculum, then swabbing gauze pad after gauze pad until a small mountain formed.The first couple pictures I have are from day 3 of using this, the last few are from today, day 5. On day 3 I lightly swabbed out the excess from the outer ear canal and all THAT is what you see on the cotton swab.The product liquifies the nastiness and it visibly drains down and out the sides of his ears, on a white cat like him you can really see just how much grossness is being flushed out. The redness improved immediately on use, and now it has completely resolved! He’s not holding his head sideways anymore, and the drainage coming out isn’t coming out looking as much like tobacco spit like it was originally, yuck!I read about the tip falling out/off of the bottle, so I wrapped it with a layer of freezer tape, it is keeping it in place perfectly snug.To administer: I burrito wrap/bundle him in a towel, scruff him lightly, pull his ear back, and hold the dropper an inch or so away so I can see the drops individually fall. If you can drop them against the skin of the outer ear avoiding the inner canal and fur it seems to lessen the head shaking instinct. For him, as a 11lb cat, I found 5 drops seems to be a good amount.He seems completely unbothered by the medicine itself. He shakes his head once or twice, I give him some treats which he eats immediately and he goes right back to be-bopping around. It doesn’t seem to have any effect on his appetite or be giving him any GI upset.Today is day 5, there is still quite a lot of buildup in the deeper part of his ear canal, I will continue with the treatment for the full 7 days, possibly extend to 10. ### ⭐⭐⭐⭐⭐ Great product. Solved my dog’s ear problem quickly. *by on Reviewed in Australia 22 February 2026* Wow!My dog had what I interpreted as excessive wax build up in his ear. He’s a feisty little guy and I could not get on top of it with mere cleaning and hair trimming. With a yeasty smell I turned to this product. The debris that came out of his ear was phenomenal, and now he is irritation free with a very clean ear canal. This product is highly recommended. ### ⭐⭐⭐⭐⭐ Works every time! *by on Reviewed in the United States 23 August 2026* About twice a year, our dog’s ears need more than just a wipe, and that’s when we turn to this product. It has successfully knocked out any and all brewing ear infections due to environmental allergies, swimming, or whatever else. Not having to pre-clean the ear means less discomfort when treating. The gel formula seems to be tolerated better by our dog than the liquid solutions, and between the post-application head shake and wiping of excess gel, it basically coats all surfaces of the inside of the ear to effectively treat the entirety. Hydrocortisone also relieves itch and calms sore, red, inflamed ears, making each subsequent application easier and less painful.If you use this please be sure to use the product for the entire duration that is recommended. This is not a one and done product. It takes time and consistency for these enzymes to fully treat, break down all the gunk, and clean out the ear. If you apply this for only 1 or 2 days, wax and debris will still remain deep inside the ear and nothing will be solved. Don’t be lazy. ## Frequently Bought Together - Zymox Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats with 1% Hydrocortisone, 1.25oz - Zymox Advanced Enzymatic Ear Wipes for Dogs and Cats - for Dirty, Waxy, Smelly Ears - Premium Strength Ear Cleaner Wipes - Non-Irritating - Hypoallergenic - 100 ct - Zymox Ear Cleanser Solution for Dogs and Cats, 4oz --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.no/products/715574302-advanced-formula-otic-plus-enzymatic-ear-solution-for-dogs-cats](https://www.desertcart.no/products/715574302-advanced-formula-otic-plus-enzymatic-ear-solution-for-dogs-cats) --- *Product available on Desertcart Norway* *Store origin: NO* *Last updated: 2026-09-16*